Muscle Relaxers and Weight Gain
While Flexeril can be an effective medication for treating muscle spasms and pain, it’s essential to be aware of potential side effects, including weight gain. If you’re experiencing weight gain or other side effects from Flexeril, don’t hesitate to reach out to Nao Medical for personalized care and support. Muscle relaxing medications are sedatives; this class of drugs includes carisoprodol, cyclobenzaprine, naproxen and diazepam.
As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. Signs and symptoms of toxicity may develop rapidly after cyclobenzaprine overdose; therefore, hospital monitoring is required as soon as possible. The acute oral LD50 of FLEXERIL is approximately 338 and 425 mg/kg in mice and rats, respectively. Told, it is the most well-tolerated muscle relaxant available.
- The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly).
- I get horrible dry mouth from it and drink water like all day all night.
- As with many prescription medications, a missed dose of methocarbamol can be taken when remembered.
- Furthermore, cardiovascular adverse reactions of TCAs are shared by Cyclobenzaprine and can yield fatal arrhythmias, sinus tachycardia, heart attack, and even stroke.
- Evidence suggests that the net effect of cyclobenzaprine is a reduction of tonic somatic motor activity, influencing both gamma (γ) and alpha (α) motor systems.
Notably, a class of type 2 diabetes drugs known asglucagon-like peptide 1 (GLP-1) agonists can cause patients to lose a significant amount of weight — around 15 or 20 percent of their body weight. Some of the more common names in this class include flexeril generic semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro). Common side effects include drowsiness, dizziness, dry mouth, and blurred vision. However, weight gain is also a potential side effect that can be concerning for some patients.
The manifestations of Flexeril overdose develop rapidly and manifest initially as drowsiness with tachycardia. Overdose can manifest with any of the adverse side effects mentioned previously in this article. Muscle relaxers do not typically affect weight directly, however some weight gain have been reported because they reduce mobility coupled with reduced physical activity from the underlying problem.
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The efficacy of FLEXERIL 5 mg was demonstrated in two seven-day, double-blind, controlled clinical trials enrolling 1405 patients. One study compared FLEXERIL 5 mg and 10 mg t.i.d. to placebo; and a second study compared FLEXERIL 5 mg and 2.5 mg t.i.d. to placebo. Primary endpoints for both trials were determined by patient-generated data and included global impression of change, medication helpfulness, and relief from starting backache. Each endpoint consisted of a score on a 5-point rating scale (from 0 or worst outcome to 4 or best outcome).
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If you started gaining weight when you began one of these medicines, then there is a chance that the medicine is at least partly to blame. Headache is a side effect of methocarbamol, but the incidence is unknown. If headaches are a problem, ask the prescribing healthcare provider for medical advice on how to handle them. Our writers and reviewers are experienced professionals in medicine, addiction treatment, and healthcare. AddictionResource fact-checks all the information before publishing and uses only credible and trusted sources when citing any medical data. The Verified badge on our articles is a trusted sign of the most comprehensive scientifically-based medical content.
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The overall effectiveness of FLEXERIL was similar to that observed in the double-blind controlled studies; the overall incidence of adverse effects was less (see ADVERSE REACTIONS). If you are concerned that a medicine is causing you to gain weight, make an appointment to talk with your provider. Never stop taking a medicine without talking with your healthcare provider first. Then during the visit, you can discuss all of your treatment choices.
For most patients, the recommended dose of Flexeril is 5 mg three times a day. People who are concerned about weight gain on medication can speak to their doctor about possible side effects. Some medications, such as corticosteroids, cause weight gain by altering the body’s metabolism and influencing water and electrolyte balances. However, a doctor will generally notify a person that they have gained weight since their previous appointment. They might ask about changes in lifestyle habits to assess whether the medication has caused the weight gain.
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Cyclobenzaprine: Side Effects, dosage, uses, and more.
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A 2011 study suggests that exercise has health benefits regardless of whether it leads to weight loss. If a medicine causes you to be tired or have shortness of breath, you might be less likely to exercise. For certain medicines, researchers aren’t exactly sure what triggers the weight gain. Skin reactions such as itching, hives, and skin rash may occur with methocarbamol, but their incidence hasn’t been determined. These reactions may be simply a bother, but they may also be a sign of an allergy to the medication.
Taking oral medication means that the drug is circulated throughout your body, not just to the site of injury. These medications can affect your body in many ways besides reducing the spasms in your injured muscles. Although muscle relaxers do not directly cause weight gain, the reduced mobility of the injury and the effects of the medications can result in weight gain as a result of decreased activity. Around one in ten people who take Lyrica (pregabalin) for medical reasons experience minimal to moderate weight gain. Weight gain may be higher in those taking the medication for diabetic peripheral neuropathy, taking higher doses, and using other medication at the same time, but can be avoided or minimized with a healthy diet and exercise. “These medications have been used for many years and are often commonplace in diabetes management, but there are newer medications that promote weight loss and should be considered,” Batsis says.